Hello, I wanted to buy a bike with GRX Di2, but Shimano already released the new Ultegra and Dura Ace, so I am wondering if there is a new GRX Di2 on the way for 2022, what do you guys think?
Probably won't be out for another year or two. Shimano groupsets only get refreshed every 5ish years and GRX isn't old enough. It might be faster than their original time frame just to bring it in line with their other Di2 groupsets, but I doubt this year.
We can only guess based on history if an updated GRX is coming. SRAM's AXS, especially the Rival level, is eating Shimano's lunch right now. Shimano would be crazy to delay it because of history.
Additionally, Shimano is really struggling to get their current stuff produced. There's mega delays for a lot of the 12 speed parts and they were announced quite some time ago. Their basic consumable items are pretty difficult to get as well.
If your real question is asking if you should delay buying a bike right now to hold out for GRX 12 speed, I would say absolutely not. It won't happen in 2022.